Sensibio Defensive serum

The long-lasting soothing moisturizing concentrate that acts against inflamm'aging caused by external aggressions.



Sensitive and sensitised skin

Defensive Technology


For whom?

Adults, Teens


View its composition

Proven efficacy

84% notice that wrinkles and fine lines appear reduced (1)

Sensibio Defensive Serum

  • Wrinkles and fine lines appear reduced (4).
  • Revives the radiance of the complexion
  • Immediately soothes
  • Moisturizes 24h
  • Light and milky texture.

Very good tolerance. Fragrance-free.
Tested under dermatological control.

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All BIODERMA products are formulated according to the ecobiology principles, which is at the heart of NAOS approach, to respect the skin's ecosystem and preserve its health in a lasting way.

Bioderma provides a unique and effective eco-biological response for sensitive and sensitized skin. DEFENSIVE technology and the fucose polymer give the skin the means to defend itself against the inflamm'aging phenomenon. They act on the various origins of sensitivity and premature aging by stopping the vicious circle responsible for the exacerbation of sensitive skin and skin aging.  

Protective action: rich in antioxidants carnosine and vitamin E to protect the skin from aggressions causing dryness

Fortifying action: tetrapeptide-10 allows an effective recovery of the skin's moisture barrier. Associated with the polymer of fucose, they improve the resistance.

Soothing action : the polyphenols of red sage limit the hyper-reactivity of the skin by hydrating the skin.


Apply morning and evening to the face and neck, ideally cleansed with a Sensibio hygiene product.

For an ideal sensitive skin routine:

  • Step 1 I remove my eye makeup with Sensibio H20 eyes
  • Step 2 I clean my face with Sensibio H20
  • Step 3 I treat inflamm'aging with Sensibio Defensive Serum
  • Step 4 I soothe with Sensibio Defensive or Sensibio Defensive Rich

ECO-CONSCIOUS PRODUCT DESIGN: We are consistently working to improve our packaging to minimize environmental impact. The majority of our products are made of 100% recyclable plastic and all of our outerboxes are made of sustainably sourced, 100 % recyclable paper. SORTING: To ensure that this item is properly recycled, please refer to your local sorting instructions.

Sensitive skin reacts more than normal skin to stimuli that are usually of no visible consequence. It experiences sensations of discomfort that may be permanent or temporary. This skin is constantly fighting against the aggressions of daily life. It no longer has the weapons to defend itself properly, which prevents it from regaining its normal threshold.

Certain environmental factors (pollution, UV, etc.) and lifestyles (stress, diet, etc.) exacerbate the reactivity of already sensitive skin. When inflammation becomes chronic, these aggressions aggravate the skin's sensitivity and accelerate the skin's aging process, called "inflamm'aging". Thus, over time, the clinical consequences worsen with an increase in wrinkles, fine lines, skin dehydration and loss of radiance.

Tested under dermatological control.

Tested under dermatological control


The skin is comfortable: 94% (1)
Intensity of unpleasant sensations: (-) 82% in 3min (2)


The skin is more luminous: 81% (1)
Moisturizes: 24h hydration (3)

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Skin is soothed: 96% (4)


The skin is more resistant to external aggressions: 83% (4)


Wrinkles and fine lines appear reduced (4)

See sources

This product was formulated according to the ecobiological approach of the NAOS Laboratories to care for you. At the heart of this product:

Skin sensitivity is natural or induced by external aggressions. This technology acts on the causes of sensitivity and prevents skin reactivity, oxidative stress and alteration of the barrier function induced by daily aggressions.

External stress can make the skin reactive and sensitive. This patented complex contributes to increase the skin’s tolerance threshold – regardless of the skin type – to help strengthen its resistance.This patent by NAOS Research was designed in Aix-en-Provence and developed in our laboratories.

See ingredients list