Cicabio Mains

The repairing balm with a second skin effect. Hands’ instant relief.

Daily skincare

Very dry hands, micro-fissures/cracks

Antalgicine™ technology


For whom?

For all the family (children older than 3 years)


View its composition

Efficacy clinically proven

-72% of micro-cracks after 28 days

  • Immediately relieves discomfort sensations
  • Second skin effect texture - 8h protection
  • Lastingly repairs* micro-fissures / cracks
  • Nourishes intensely
  • Non-sticky, non-greasy texture

*promotes epidermal repair

See sources

All BIODERMA products are formulated according to the ecobiology principles, which is at the heart of NAOS approach, to respect the skin's ecosystem and preserve its health in a lasting way.



  • RELIEVES: Antalgicine™ is an exclusive biomimetic technology from Bioderma, inspired by our own internal mechanisms, that reduces discomfort sensations. It provides Cicabio Mains with a real ability to relieve discomfort and itching sensations linked to micro-fissures and micro-cracks.
  • PROTECTS: Cicabio Mains’ innovative texture, inspired by skin hydrolipidic film, creates an insulating yet breathable biomimetic barrier that protects the skin from external aggressions and maintains a humid environment, favourable to the natural wound healing process. It contains biomimetic lipids & hyaluronic acid to strengthen the skin barrier.


  • REPAIRS: Two complementary restructuring agents (Lipo-Koline = Phosphatidylcholine derivative and Lipo-AA = Hydroxyproline Amino acid derivative) promote skin repair at different levels.

Hands and nails

Apply as often as necessary with a gentle massage

  • Step 1 Wash your hands with Atoderm Huile de douche.
  • Step 2 Apply Cicabio Mains to hands skin.
  • Step 3 Gently massage until absorbed.

Apply as often as necessary with a gentle massage

  • Step 1 Wash your hands with Atoderm Huile de douche.
  • Step 2 Apply Cicabio Mains to hands skin.
  • Step 3 Gently massage until absorbed.
  • Step 4 Use in addition with a medical treatment prescribed by your doctor.

Do not use on significant skin wounds or exudates.

If skin irritation persists, consult a healthcare professional.

ECO-CONSCIOUS PRODUCT DESIGN: We are consistently working to improve our packaging to minimize environmental impact. The majority of our products are made of 100% recyclable plastic and all of our outerboxes are made of sustainably sourced, 100 % recyclable paper. SORTING: To ensure that this item is properly recycled, please refer to your local sorting instructions.

Damaged hands is a common condition that manifests itself through micro-fissures, micro-cracks, redness, severe dryness, itching, and sensations of discomfort. Anyone can have damaged hands, regardless of age and gender and some factors expose to a greater risk: 1) Extreme temperatures 2) Having wet hands, because of a professional or personal occupation (health care professionals, cook, hairdresser, etc.) and because of repeated hand washing 3) Using household/chemical products without gloves (factory workers, cleaning ladies 4) Oversolicited hands because of a manual job or activity (carpenter, gardener...) 5) A chronic skin disease or allergies (allergic contact dermatitis, irritative contact dermatitis...). The global epidemic of COVID-19 and the repetition of barrier gestures all day long can also severely damage the hands. It is difficult to find repairing hand creams that are both effective and pleasant to apply.

Tested under dermatological control

The skin is immediately relieved: 91% (1)

The skin is protected: 66% insulating power (2)

The product allows to get back to its activity immediately after application: 97% (1)

See sources

The skin is repaired: 100% (1)

72% of micro-cracks after 28 days(3)

See sources

This product was formulated according to the ecobiological approach of the NAOS Laboratories to care for you. At the heart of this product:

This technology helps decrease discomfort. This technology by NAOS Research was designed in Aix-en-Provence and developed in our laboratories.

See ingredients list